Ovar

Primärtherapie

AGO-OVAR 1/2

Phase I/II study of the combination of carboplatin and paclitaxel as first-line therapy patients with advanced epithelial ovarian cancer

 

A. du Bois, H.-J. Lück, T. Bauknecht, V. Möbus, H. Bochtler, K. Diergarten & H.-G. Meerpohl

 

Annals of Oncology 8: 335-361 (1997)

 

 

AGO-OVAR 3

A Randomized Clinical Trial of Cisplatin/Paclitaxel Versus Carboplatin/Paclitaxel as First-Line Treatment of Ovarian Cancer

 

du Bois A, Lück H.-J, Meier W, Adams H-P, Möbus V, Costa S, Bauknecht T, Richter B, Warm M, Schröder W, Olbricht S, Nitz U, Jackisch C, Emons G, Wagner U, Kuhn W, Pfisterer J, for the Arbeitsgemeinschaft Gynäkologische Onkologie (AGO) Ovarian Cancer Study Group

 

J Natl Cancer Inst 2003; 95:1320-30

 

 

AGO-OVAR 4

First-line chemotherapy with epirubicin, paclitaxel, and Carboplatin (ET-Carbo) for advanced ovarian carcinoma. A phase I/II study of the Arbeitsgemeinschaft Gynäkologische Onkologie (AGO) Ovarian Cancer Study Group

 

A du Bois, HJ Lück, T Bauknecht, W Meier, B Richter, J Pfisterer, J Quaas, W Kuhn

 

J Clin Oncol 17: 46-51, 1999

 

 

AGO-OVAR 5

Addition of epirubicin as third drug to carboplatin-paclitaxel in firstline treatment of advanced ovarian cancer. ...

 

du Bois A, Weber B, Rochon J, Meier W, Goupil A, Olbricht S, Barats Jean-Claude, Kuhn W, Orfeuvre H, Wagner U, Richter B, Lueck HJ, Pfisterer J, Costa S, Schroeder W, Kimmig R, Pujade-Lauraine E for AGO-OVAR and GINECO

 

J Clin Oncol 24: 1127-1135

 

 

AGO-OVAR 6

Docetaxel and carboplatin as first-line chemotherapy in patients with advanced gynecological tumors. A phase I/II trial of the Arbeitsgemeinschaft Gynäkologische Onkologie (AGO-OVAR) Ovarian Cancer Study Group

 

Pfisterer J, du Bois A, Wagner U, Quaas J, Blohmer JU, Wallwiener D and Hilpert F

 

Gynecologic Oncology 92 (2004) 949-956

 

 

AGO-OVAR 7

Randomized Phase III Trial of Topotecan Following Carboplatin and Paclitaxel in First-line Treatment of Advanced Ovarian Cancer: A Gynecologic Cancer

Intergroup Trial of the AGO-OVAR and GINECO

 

Pfisterer J, Weber B, Reuss A, Kimmig R, du Bois A, Wagner U, Bourgeois H, Meier W, Costa S, Blohmer JU, Lortholary A, Olbricht S, Stähle A, Jackisch C, Hardy-Bessard AC, Möbus V, Quaas J, Richter B, Schröder W, Geay JF, Lück HJ, Kuhn W, Meden H, Nitz U, Pujade-Lauraine E for the AGO-OVAR and GINECO

 

J Natl Cancer Inst 2006; 98:1036-1045

 

 

AGO-OVAR 8

A phase II study of paclitaxel, carboplatin, and gemcitabine in previously untreated patients with epithelial ovarian cancer FIGO stage IC-IV (AGO-OVAR protocol OVAR-8)

 

du Bois A, Belau A, Wagner U, Pfisterer J , Schmalfeldt B, Richter B, Stähle A, Jackisch C, Lueck H-J, Schroeder W, Olbricht S, Elser G and for the Arbeitsgemeinschaft Gyneaekologische Onkologie Ovarian Cancer Study Group (AGO-OVAR)

 

Gynecol Oncol 96 (2005) 444-451

 

 

AGO-OVAR 9

Phase III Trial of Carboplatin Plus Paclitaxel With or Without Gemcitabine in First-Line Treatment of Epithelial Ovarian Cancer

 

du Bois A, Herstedt J, Hardy-Bessard A-C, Müller H-H, Harter P, Kristensen G, Joly F, Huober J, Avall-Lundqvist E, Weber B, Kurzeder C, Jelic S, Pujade-Lauraine E, Burges A, Pfisterer J, Gropp M, Staehle A, Wimberger P, Jackisch C, Sehouli J

 

J Clin Oncol 28: 4162-4169 (2010)

 

 

AGO-OVAR 10

Abagovomab as Maintenance Therapy in Patients with Epithelial Ovarian Cancer (MIMOSA Study): A Phase III Trial of the AGO OVAR,
COGI, GINECO, and GEICO - The MIMOSA Study

 

Sabbatini P, Harter P, Scambia G, Sehouli J, Meier W, Wimberger P, Baumann KH, Kurzeder C, Schmalfeldt B, Cibula D, Bidzinski M, Casado A, Martoni A, Colombo N, Holloway RW, Selvaggi L, Li A, del Campo J, Cwiertka K, Pinter T, Vermorken JB, Pujade-Lauraine E, Scartoni S, Bertolotti M, Simonelli C, Capriati A, Maggi CA, Berek JS, Pfisterer J

 

J Clin Oncol 2013: 1554-1561

  

 

AGO-OVAR 11

A Phase 3 Trial of Bevacizumab in Ovarian Cancer

 

Perren, TJ, Swart AM, Pfisterer J, Ledermann JA, Pujade-Lauraine E, Kristensen G, Carey MS, Beale P, Cervantes A, Kurzeder C, du Bois A, Sehouli J, Kimmig R, Stähle A, Collinson F, Essapen S, Gourley C, Lortholary A, Selle F, Mirza MR, Leminen A, Plante M, Stark D, Qian W, Parmar M KB, Oza AM, for the ICON7 Investigators

 

N Engl J Med 2011;365:2484-96

 

 

Standard chemotherapy with or without bevacizumab in advanced ovarian cancer: quality-of-life outcomes from the International Collaboration on Ovarian Neoplasms (ICON7) phase 3 randomised trial

 

Stark D, Nankivell M, Pujade-Lauraine E, Kristensen G, Elit L, Stockler M,  Hilpert F, Cervantes A, Brown J, Lanceley A, Velikova G, Sabate E, Pfisterer J, Carey MS, Beale P, Qian W, Swart AM, Oza A, Perren T

 

Lancet Oncol 2013;14: 236-243

  

 

Standard chemotherapy with or without bevacizumab for women with newly diagnosed ovarian cancer (ICON7): overall survival results of a phase 3 randomised trial

 

Oza AM, Cook AD, Pfisterer J, Embleton A, Ledermann JA, Pujade-Lauraine E, Kristensen G, Carey MS, Beale P, Cervantes A, Park-Simon T-W, Rustin G, Joly F, Mirza MR, Plante M, Quinn M, Poveda A, Jayson GC, Stark D, Swart AM, Farrelly L, Kaplan R, Parmar MKB, Perren TJ, for the ICON7 trial investigators

 

Lancet Oncol 2015;16:928-36

 

AGO-OVAR 11t

Spezialisierte histopathologische Zweitbegutachtung fortgeschrittener Ovarialkarzinome

S. Kommoss, J. Pfisterer, A. du Bois, D. Schmidt, F. Kommoss

 

Pathologe 2014, 35:355-360

 

 

Bevacizumab may differentially improve ovarian cancer outcome in patients with proliferative and mesenchymal molecular subtype

 

Kommoss S, Winterhoff B, Oberg AL, Konecny G, Wang C, Riska SM, Fan JB, Maurer MJ, Craig A, Shridhar V, Kommoss F, du Bois A, Hilpert F, Mahner S, Baumann K, Schröder W, Burges A, Canzler U, Chien J, Embleton AC, Parmar M, Kaplan R, Perren T, Hartmann LC, Goode EL, Dowdy SC and Pfisterer J

 

Clin Cancer Res 2017 Jul 15;23(14):3794-3801

 

 

 

AGO-OVAR 12

A Randomised Placebo-Controlled GCIG/ENGOT-Intergroup Phase III Trial of Standard Frontline Chemotherapy +/- Nintedanib for Advanced Ovarian Cancer

 

du Bois A, Kristensen G, Ray-Coquard I, Reuss A, Pignata S, Colombo N, Denison U, Vergote I, del Campo JM, Ottevanger P, Heubner M, Minarik T, Sevin E, de Gregorio N, Bidzinski M, Pfisterer J, Malander S, Hilpert F, Mirza MR, Sambia G, Meier W, Nicoletto MO, Bjørge L, Lortholary A, Sailer MO, Merger M, Harter P, on behalf of the AGO Study Group led Gynecologic Cancer Intergroup (GCIG) / European Network of Gynaecologic Oncology Trials Group (ENGOT) Intergroup Consortium

 

Published online November 15, 2015: DOI: http://dx.doi.org/10.1016/S1470-2045(15)00366-6

 

 

Nintedanib and ovarian cancer: standardise surgery in trials?

Kehoe S

Published online November 15, 2015: http://dx.doi.org/10.1016/S1470-2045(15)00398-8

 

 

 

AGO-OVAR 15

Randomized Phase II Trial of Carboplatin and Paclitaxel with or without Lonafarnib in First-Line Treatment of Epithelial Ovarian Cancer Stage IIB-IV

 

Meier W, du Bois A,  Rau J, Gropp M, Baumann KH, Huober J, Wollschlaeger K, Kreienberg R, Canzler U, Schmalfeldt B, Wimberger P, Richter B, Schröder W, Belau A, Stähle A, Burges A, Sehouli J

 

Gynecologic Oncology 126 (2012) 236–240

 

 

 

AGO-OVAR 16

Incorporation of Pazopanib in Maintenance Therapy of Ovarian Cancer

 

du Bois A, Floquet A, Kim J-W, Rau J, del Campo JM, Friedlander M, Pignata S, Fujiwara K, Vergote I, Colombo N, Mirza MR, Monk BJ, Kimmig R, Ray-Coquard I, Zang R, Diaz-Padilla I, Baumann KH, Mouret-Reynier M-A, Kim J-H, Kurzeder C, Lesoin A, Vasey P, Marth C, Canzler U, Scambia G, Shimada M, Calvert P, Pujade-Lauraine E, Kim B-G, Herzog TJ, Mitrica I, Schade-Brittinger C, Wang Q, Cressenzo R, Harter P

 

J Clin Oncol. 2014 Oct 20; 32:3374-82, doi: 10.1200/JCO.2014.55.7348, Epub 2014 Sep 15

 

 

Progression-free survival by local investigator versus independent central review: comparative analysis of the AGO-OVAR 16 trial

 

Floquet A, Vergote I, Colombo N, Fiane B, Monk BJ, Reinthaller A, Calvert P, Herzog TJ, Meier W, Kim JW, del Campo JM, Friedlander M, Pisano C, Ionishi S, Crescenzo R J, Barrett C, Wang K,  Mitrica I, du Bois A

 

Gynecologic Oncology 136 (2015) 37-42, DOI: http://dx.doi.org/10.1016/j.ygyno.2014.11.074

 

 

BRCA1/2 mutations associated with progression free survival in ovarian cancer patients in the AGO-OVAR 16 study

 

Harter P, Johnson T, Berton-Rigaud D, Park SY, Friedlander M, del Campo JM, Shimada M, Forget F, Mirza MR, Colombo N, Zamagni C, Chan JK, Imhof M, Herzog TJ, O'Donnell D, Heitz F, King K, Stinnett S, Barrett C, Jobanputra M, XU CF, du Bois A

 

Gynecol Oncol 2016 Mar; 140(3): 443-9. doi: 10.1016/j.ygyno.2015.12.027. Epub 2015 Dec 29

 

 

Communicating BRCA Research Results to Patients Enrolled in International Clinical Trials: Lessons Learnt From the AGO-OVAR 16 Study

 

Pulford D, Harter P, Floquet A, Barrett C, Suh DH, Friedlander M, Arranz JA, Hasegawa K, Tada H, Vuylsteke P, Mirza MR, Donadello N, Scambia G, Johnson T, Cox Ch, Chan JK, Imhof M, Herzog TJ, Calvert P, Wimberger P, Berton-Rigaud D, Lim MC, Elser G, Xu CF, du Bois A

 

BMC Medical Ethics (2016) 17:63, DOI: 10.1186/s12910-016-0144-y

 

 

 

Rezidivtherapie

AGO-OVAR 2.1

Chemotherapy versus Hormonal Treatment in Platinum- and Paclitaxel-Refractory Ovarian Cancer: A Randomized Trial of the German Arbeitsgemeinschaft Gynaekologische Onkologie (AGO) Study Group Ovarian Cancer

 

A du Bois, W Meier, HJ Lück, G Emons, V Möbus, W Schröder, S Costa, T Bauknecht, S Olbricht, C Jackisch, B Richter, U Wagner

 

Annals of Oncology 13:251-257,2002

 

 

AGO-OVAR 2.2

Paclitaxel plus platinum-based chemotherapy versus conventional platinum-based chemotherapy in women with relapsed ovarian cancer: the ICON4/AGO-OVAR 2.2 trial

The ICON and AGO Collaborators (writing committee)

 

Lancet 361: 2099-2106 (2003)

 

 

AGO-OVAR 2.3
Topotecan versus treosulfan, an alkylating agent, in patients with epithelial ovarian cancer and relapse within 12 months following 1st-line platinum/paclitaxel chemotherapy. A prospectively randomized phase III trial by the Arbeitsgemeinschaft Gynaekologische Onkologie Ovarian Cancer Study Group (AGO-OVAR)

 

W Meier, A du Bois, A Reuss, W Kuhn, S Olbricht, M Gropp, B Richter, HJ Lück, R Kimmig, J Pfisterer

 

Gynecologic Oncology 114 (2009) 199-205

 

 

AGO-OVAR 2.4

2nd-line chemotherapy with carboplatin and gemcitabine in patients with platinum sensitive recurrent ovarian cancer. A phase I/II study of the Arbeitsgemeinschaft Gynäkologische Onkologie (AGO) Ovarian Cancer Study Group

 

A du Bois, HJ Lück, J Pfisterer, W Schroeder, JU Blohmer, R Kimmig, V Moebus, J Quaas

 

Annals of Oncology 12: 1115-1120, 2001

 

 

AGO-OVAR 2.5

Gemcitabine plus carboplatin versus carboplatin in patients with platinum-sensitive-recurrent ovarian cancer

 

Pfisterer J, Plante M, Vergote I, Zimmerman A, du Bois A, Hirte H, Lacave A J, Wagner U, Stähle A, Stuart G, Kimmig R, Olbricht S, Le T, Emerich J, Kuhn W, Bentley J, Jackisch C, Lück H-J, Rochon J, Zimmermann A H, Eisenhauer E for the AGO OVAR, NCIC CTG and EORTC GCGPfisterer J, Plante M, Vergote I, Zimmerman A, du Bois A, Hirte H, Lacave A J, Wagner U, Stähle A, Stuart G, Kimmig R, Olbricht S, Le T, Emerich J, Kuhn W, Bentley J, Jackisch C, Lück H-J, Rochon J, Zimmermann A H, Eisenhauer E for the AGO OVAR, NCIC CTG and EORTC GCG

 

J Clin Oncol 24:4699-4707, 2006

 

 

AGO-OVAR 2.6

Gefitinib in combination with tamoxifen in patients with ovarian cancer refractory or resistant to platinum-taxane based therapy – A phase II trial of the AGO Ovarian Cancer Study Group (AGO-OVAR 2.6)

 

Wagner U, du Bois A, Pfisterer J, Huober J, Loibl S, Lück HJ, Sehouli J, Gropp M, Stähle A, Schmalfeldt, B, Meier W, Jackisch C

 

Gynecol Oncol 2007; 105:132-137

 

 

AGO-OVAR 2.8

The anti-idiotypic antibody abagovomab in patients with recurrent ovarian cancer - A phase I trial of the AGO-OVAR

 

Pfisterer J, du Bois A, Sehouli J, Loibl S, Reinartz S, Reuß A, Canzler U, Belau A, Jackisch C, Kimmig R, Wollschlaeger K, Heilmann V, Hilpert , On behalf of the AGO-OVAR

 

Ann Oncol 17: 1568-1577, 2006

 

 

AGO-OVAR 2.9

Pegylated liposomal doxorubicin and carboplatin compared with paclitaxel an carboplatin for patients with platinum-sensitive ovarian cancer in late relapse

 

Pujade-Lauraine E, Wagner U, Aavall-Lundqvist E, Gebski V, Heywood M, Vasey P A, Volgger B, Vergote I, Pignata S, Ferrero A, Sehouli J, Lortholary A, Kristensen G, Jackisch C, Joly F, Brown C, Le Fur N, and du Bois A

 

J Clin Oncol 28:3323-3329, 2010

 

 

Carboplatin and pegylated liposomal doxorubicin versus carboplatin and paclitaxel in very platinum-sensitive ovarian cancer patients: results from a subset analysis of the CALYPSO phase III trial

 

Mahner S, Meier W, du Bois A, Brown C, Lorusso D, Dell’Anna T, Cretin J, Havsteen H, Besette P, Zeimet AG, Vergote I, Vasey P, Pujade-Lauraine E, Gladieff L, Ferrero AM

 

European Journal of Cancer (2015) 51, 352-358

 

 

AGO-OVAR 2.10

Intraperitoneal treatment with the trifunctional bispecific antibody Catumaxomab in patients with platinum-resistant epithelial ovarian cancer: A phase IIa study of the AGO Study Group

 

Baumann K, Pfisterer J, Wimberger P, Burchardi N, Kurzeder C, du Bois A, Loibl S, Sehouli J, Huober J, Schmalfeldt B, Vergote I, Lück HJ, Wagner U

 

Gynecol Oncol 2011; 123:27-32

 

 

AGO-OVAR 2.11

A Phase II Trial (AGO 2.11) in platinum resistant Ovarian Cancer: a randomized multicenter trial with Sunitinib (SU11248) to evaluate dosage, schedule, tolerability, toxicity and effectiveness of a multitargeted receptor tyrosine kinase inhibitor monotherapy

 

Baumann K, du Bois A, Meier W, Rau J, Wimberger P, Sehouli J, Kurzeder C, Hilpert F, Hasenburg A, Canzler U, Hanker LC, Hillemanns P, Richter B, Wollschlaeger K, Dewitz T, Bauerschlag D, Wagner U

 

Annals of Oncology 23:2265-2271, 2012

 

 

AGO-OVAR 2.12

Topotecan plus carboplatin versus standard therapy with paclitaxel plus carboplatin (PC) or gemcitabine plus carboplatin (GC) or pegylated liposomal doxorubicin plus carboplatin (PLDC): a randomized phase III trial of the NOGGO-AGO Study Group-AGO Austria and GEICO-ENGOT-GCIG intergroup study (HECTOR)

 

Sehouli J, Chekerov R, Reinthaller A, Richter R, Gonzalez-Martin A, Harter P, Woopen H, Petru E, Hanker LC, Keil E, Wimberger P, Klare P, Kurzeder C, Hilpert F, Belau AK, Zeimet A, Bover-Barcelo I, Canzler U, Mahner S, Meier W

 

Ann Oncol. (2016) 27 (12):2236-2241

 

 

AGO-OVAR 2.13

Addition of vandetanib to pegylated liposomal doxorubicin (PLD) in patients with recurrent ovarian cancer. A randomized phase I/II study of the AGO Study Group (AGO-OVAR 2.13)

 

Philipp Harter, Jalid Sehouli, Rainer Kimmig, Jörn Rau, Felix Hilpert, Christian Kurzeder, Gabriele Elser, Andreas du Bois

 

Invest New Drugs (2013) 31:1499-1504

 

 

AGO-OVAR 2.15

Bevacizumab combined with chemotherapy for platinum-resistant recurrent ovarian cancer: The AURELIA open-label randomized phase III trial

 

Pujade-Lauraine E, Hilpert F, Weber B, Reuss A, Poveda A, Kristensen G, Sorio R, Vergote I, Witteveen P, Bamias A, Pereira D, Wimberger P, Oaknin A, Mirza MR, Follana P, Bollag D, Ray-Coquard I on behalf of the ENGOT-GCIG investigators

 

J Clin Oncol 32:1302-1308, 2014; DOI:10.1200/JCO.2013.51.4489

 

 

 

Patient reported outcome resuluts from the open-label phase III AURELIA trial evaluating bevacizumab-containing therapy for platinum-resistant ovarian cancer

 

Stockler MR, Hilpert F, Friedlander M, King MT, Wenzel L, Lee C, Joly F, de Gregorio N, Arranz JA, Mirza MR, Sorio R, Freudensprung U, Sneller V, Hales G, Pujade-Lauraine E

 

J Clin Oncol 43:1309-1316,2014; DOI: 10.1200/JCO.2013.51.4240

  

 

 

Editorial Emerging Role for Bevacizumab in Combination With Chemotherapy for Patients With Platinum-Resistant Ovarian Cancer

 

Joyce F. Liu and Stephen A. Cannistra

 

J Clin Oncol 2014, Mar 17 [Epub ahead of print]; DOI:10.1200/JCO.2013.54.7299

 

 

Bevacizumab combined with weekly Paclitaxel, Pegylated Liposomal Doxurubicin, or Topotecan in platinum-resistend recurrent ovarian cancer: Analysis by chemotherapy cohort of the randomized Phase III AURELIA trial

 

Poveda A, Selle F, Hilpert F, Reuß A, Savarese A, Vergote I, Witteveen P, Bamias A, Scotto N, Mitchell L, Pujade-Lauraine E

 

J Clin Oncol 2015 33(32):3836-8

doi: 10.1200/JCO.2015.63.1408.Epub 2015 Aug 17

http://jco.ascopubs.org/content/early/2015/08/11/JCO.2015.63.1408.full

 

  

AGO-OVAR 2.16 / MITO 8

 

Randomized controlled trial testing the efficacy of platinum-free interval prolongation in advanced ovarian cancer

 

Pignata S, Scambia G, Bologna A, Signoriello S, Vergote I, Wagner U, Lorusso D, Murgia V, Sorio R, Ferrandina G, Sacco C, Cormio G, Breda E, Cinieri S, Natale D, Mangili G, Pisano C, Cecere SC, Di Napoli M, Salutari V, Raspagliesi F, Arenare L, Bergamini A, Bryce JC, Gennaro D, Piccirillo MC, Gallo C, Perrone F

 

J Clin Oncol. 2017 Oct 10;35(29):3347-3353.

doi: 10.1200/JCO.2017.73.4293. Epub 2017 Aug 21


 

AGO-OVAR 2.17

Olaparib combined with chemotherapy for recurrent platinum-sensitive ovarian cancer: a randomised phase 2 trial

 

Amit M Oza, David Cibula, Ana Oaknin Benzaquen, Christopher Poole, Ron HJ Mathijssen, Gabe S Sonke, Nicoletta Colombo, Jiri Spacek, Peter Vuylsteke, Holger Hirte, Sven Mahner, Marie Plante, Barbara Schmalfeldt, Helen Mackay, Jacqui Rowbottom, Elisabeth S Lowe, Brian Dougherty, J Carl Barrett, Michael Friedlander

 

The Lancet Oncology, Volume 16, Issue 1, 87 - 97 

http://dx.doi.org/10.1016/S1470-2045(14)71135-0

 

 

AGO-OVAR 2.19/TRINOVA-2

ENGOT-ov-6/TRINOVA-2: Randomized, double-blind, phase 3 study of pegylated liposomal doxorubicin plus trebananib or placebo in women with recurrent partially platinum-sensitive or resistant ovarian cancer

 

Marth C, Vergote I, Scambia G, Oberaigner W, Clamp A, Berger R, Kurzeder C, Colombo N, Vuylsteke P, Lorusso D, Hall M, Renard V, Pignata S, Kristeleit R, Sevilay A, Rustin G, Wenham RM, Mirza M, Fong PC, Oza A, Monk BJ, Ma H, Vogl FK, Bach BA

European Journal of Cancer 70 (2017) 111-121

DOI: http://dx.doi.org/10.1016/j.ejca.2016.09.004

 

 

 

AGO-OVAR 2.20

Double-Blind, Placebo-Controlled, Randomized Phase III Trial Evaluating Pertuzumab Combined With Chemotherapy for Low Tumor Human Epidermal Growth Factor Receptor 3 mRNA-Expressing Platinum-Resistant Ovarian Cancer (PENELOPE)

 

Kurzeder C, Bover I, Marmé F, Rau J, Pautier P, Colombo N, Lorusso D, Bjurberg M, Marth C, Barretina-Ginesta P, Vergote I, Floquet A, del Campo JM, Mahner S, Bastiere-Truchot L, Martin N, Oestergaard MZ, Kiermaier A, Schade-Brittinger C, Polleis S, du Bois A and Gonzalez-Martin A

J Clin Oncol. 2016 Jul 20;34(21):2516-25. doi:10.1200/JCO.2015.66.0787. Epub 2016 Jun 6

 

 

Pertuzumab Plus Chemotherapy for Platinum-Resistant Ovarian Cancer: Safety Run-in Results of the PENELOPE Trial

 

González-Martín A, Pautier P, Mahner S, Rau J, Colombo N, Ottevanger P, del Campo JM, Selle F, du Bois A, Gadducci A, Garcia Y, Berton-Rigaud D, Marmé F, Ortega E, Martin N, Bastiere-Truchot L, Kiermaier A, Kurzeder C

 

Int J Gynecol Cancer. 2016 Jun;26(5):898-905. doi: 10.1097/IGC.0000000000000695

 

 

AGO-OVAR 2.22/NOVA

Niraparib Maintenance Therapy in Platinum-Sensitive Recurrent Ovarian Cancer

 

Mirza MR, Monk B, Herrstedt J, Oza A, Mahner S, Redondo A, Fabbro M, Ledermann J, Lorusso K, Vergote I, Ben-Baruch EN, Marth C, Madry R, Christensen.., Berek J, Dørum A, Tinker A, du Bois A, Gonzalez M, Fallana P, Benigno B, Rosenberg P, Gilbert L, Rimel B, Buscema J, Balser J, Agarwal S, Matulonis U

 

N Engl J Med 2016; Published online 8. Oktober 2016

DOI 10.1056/NEJMoa1611310

 

 

AGO-OVAR 2.23/SOLO 2

Olaparib tablets as maintenance therapy in patients with platinum-sensitive, relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT-Ov21): a double-blind, randomised, placebo-controlled, phase 3 trial

 

Pujade-Lauraine E, Ledermann JA, Selle F, Gebski V, Penson RT, Oza AM, Korach J, Huzarski T, Poveda A, Pignata S, Friedlander M, Colombo N, Harter P, Fujiwara K, Ray-Coquard I, Banerjee S, Liu J, Lowe ES, Bloomfield R, Pautier P, the SOLO2/ENGOT-Ov21 investigators

 

Published Online July 25, 2017 http://dx.doi.org/10.1016/S1470-2045/17)30469-2

 

 

 


 

Uterus

AGO GYN 2

Pegylated liposomal doxorubicin and carboplatin in advanced gynecologic tumors: a prospective phase I/II study of the Arbeitsgemeinschaft Gynaekologische Onkologie Studiengruppe Ovarialkarzinom (AGO-OVAR)

 

A. du Bois, A. Burges, W. Meier, J. Pfisterer, B. Schmalfeldt, B. Richter, C. Jackisch, A. Staehle, R. Kimmig & G. Elser on behalf of AGO-OVAR Germany

 

Annals of Oncology 17: 93-96, 2006

 

 

AGO GYN 3

Combination Therapy with Pegylated Liposomal Doxorubicin and Carboplatin in Gynecologic Malignancies: A Prospective Phase-II Study of the Arbeitsgemeinschaft Gynaekologische Onkologie Studiengruppe Ovarialkarzinom (AGO-OVAR) and Kommission Uterus (AGO-K-Ut)

 

du Bois A, Pfisterer J, Burchardi N, Loibl S, Huober J, Wimberger P, Burges A, Staehle A, Jackisch C, Koelbl H

 

Gynecol Oncol 2007; 107: 518-525

 

 

AGO GYN 4

A Phase I open-label dose-escalation study of oral BIBF 1120 combined with standard paclitaxel and carboplatin in patients with advanced gynecological malignancies

 

du Bois A, Huober J, Stopfer P, Pfisterer J, Wimberger P, Loibl S Reichardt V, Harter P

 

Annals of Oncol 2010 21:370-375

 

 

AGO GYN 5

Efficiacy and Safety of AEZS-108 (LHRH Agonist Linked to Doxorubicin) in Women With Advanced or Recurrent Endometrial Cancer Expressing LHRH Receptors, A Multicenter Phase 2 Trial (AGO-GYN 5)

 

Günter Emons, Grigor Gorchev, Philipp Harter, Pauline Wimberger, Anne Stähle, Lars Hanker, Felix Hilpert, Matthias W. Beckmann, Peter Dall, Carsten Gründker, Herbert Sindermann, Jalid Sehouli

 

Int J Gynecol Cancer 2014; 24, Number 2: 260-265

 

 

Efficacy and safety of AEZS-108 (INN: Zoptarelin Doxorubicin Acetate) an LHRH agonist linked to doxorubicin in women with platinum refractory or resistant ovarian cancer expressing LHRH receptors: A multicenter Phase II trial of the ago-study group (AGO GYN 5)

 

Günter Emons, Grigor Gorchev, Jalid Sehouli, Pauline Wimberger, Anne Stähle, Lars Hanker, Felix Hilpert, Herbert Sindermann, Carsten Gründker, Philipp Harter

 

Gynecol Oncol 133 (2014): 427-432

 

 

AGO GYN 6

Open-label feasibility study of pazopanib, carboplatin, and paclitaxel in women with newly diagnosed, untreated, gynaecologic tumours: a phase I/II trial of the AGO study group

du Bois A, Vergote I, Wimberger P, Ray-Coquard I, Harter P, Baylor Curtis L, Mitrica I

 

British Journal of Cancer 2012; 106, 629-632

 

 

AGO GYN 7

Phase II Study Evaluating PegLiposomal Doxorubicin and Carboplatin Combination Chemotherapy in Gynecologic Sarcomas and Mixed Epithelial-Mesenchymal Tumors

A Phase II Protocol of the Arbeitsgemeinschaft Gynaekologische Onkologie Study Group (AGO-GYN 7)

 

Philipp Harter, Jalid Sehouli, Alexander Reuss, Klaus Baumann, Lars Hanker, Rainer Kimmig, Willibald Schröder, Alexander Burges, Martina Gropp-Meier, Christian Kurzeder, Sven Mahner, Ulrich Canzler, Hans-Joachim Lück, Werner Meier, Tanja Fehm, and Andreas du Bois

 

Int J Gynecol Cancer. 2016 Nov; 26(9):1636-1641. DOI:10.1097/IGC.0000000000000831. Epub 2016 Sep 19

 

 

 

AGO GYN 8

Temsirolismus in women with platinum-refractory/resistant ovarian cancer or advanced/recurrent endometrial carcinoma. A phase II study of the AGO-study group (AGO-GYN 8)

 

Emons G, Kurzeder C, Schmalfeldt B, Neuser P, de Gregorio N, Pfisterer J, Park-Simon TW, Mahner S, Schröder W, Lück HJ, Heubner ML, Hanker L, Thiel F, Hilpert F

 

Gynecol Oncol. 140 (2016) 450-456

 

 

 


 

Vulva

 

AGO-CaRE 1

Adjuvant Therapy in Lymph Node–Positive Vulvar Cancer: The AGO-CaRE-1 Study

 

Sven Mahner, Julia Jueckstock, Felix Hilpert, Petra Neuser, Philipp Harter, Nikolaus de Gregorio, Annette Hasenburg, Jalid Sehouli, Annika Habermann, Peter Hillemanns, Sophie Fuerst, Hans-Georg Strauss, Klaus Baumann, Falk Thiel, Alexander Mustea, Werner Meier, Andreas du Bois, Lis-Femke Griebel, Linn Woelber; for the AGO-CaRE 1 investigators

JNCI J Natl Cancer Inst (2015) 107(3):dju426 

 

 

Propensity Scoring after Multiple Imputation in a Retrospective Study on Adjuvant Radiation Therapy in Lymph-Node Positive Vulvar Cancer

 

Eulenburg C, Suling A, Neuser B, Reuss A, Canzler U, Fehm T, Luyten A, Hellriegel M, Woelber L, Mahner S

PLoS ONE 11(11): e0165705.doi: 10.1371/journal.pone.0165705

 

 

Role of tumor-free margin distance for loco-regional control in vulvar cancer - a subset analysis of the AGO CaRE-1 multicenter study

 

Wölber L, Griebel LF, Eulenburg C, Sehouli J, Jückstock J, Hilpert F, de Gregorio N, Hasenburg A, Ignatov A, Hillemanns P, Fürst S, Strauss HG, Baumann KH, Thiel F, Mustea A, Meier W, Harter P, Wimberger P, Hanker LC, Schmalfeldt B, Canzler U, Fehm T, Luyten A, Hellriegel M, Kosse J, Heiss C, Hantschmann P, Mallmann P, Tanner B, Pfisterer J, Richter B, Neuser P, Mahner S

European Journal of Cancer 69 (2016):180 - 188

http://dx.doi.org/10.1016/j.ejca.2016.09.038

 

 

Outcome after Sentinel lymph node dissection in vulvar cancer. A subgroup analysis of the AGO-CaRE-1-study

 

Klapdor R, Hillemanns P, Jückstock J, Wölber L, Hilpert F, de Gregorio N, Iborra S, Sehouli J, Habermann A, Fürst ST, Strauß HG, Baumann K, Thiel F, Mustea A, Meier W, Harter P, Wimberger P, Hanker L, Schmalfeldt B, Canzler U, Fehm T, Luyten A, Hellriegel M, Kosse J, Heiss C, Hantschmann P, Mallmann P, Tanner B, Pfisterer J, Richter B, Jäger M, Mahner S

Ann Surg Oncol (2017) 24:1314

 

  


 

Operative Fragestellungen

 

AGO-OVAR OP.1/DESKTOP I

Surgery in recurrent ovarian cancer - The Arbeitsgemeinschaft Gynaekologische Onkologie (AGO) DESKTOP OVAR trial

 

Harter P, du Bois A, Hahmann M, Hasenburg A, Burges A, Loibl S, Gropp M, Huober J, Fink D, Schröder W, Muenstedt K, Schmalfeldt B, Emons G, Pfisterer J, Wollschlaeger K, Meerpohl HG, Breitbach GP, Tanner B, Sehouli J. Heilmann V for the Arbeitsgemeinschaft Gynaekologische Onkologie Ovarian Committee (AGO OC) and the AGO Ovarian Cancer Study Group (AGO-OVAR)

 

Ann Surg Oncol 2006 online first 10-2006

 

 

AGO-OVAR OP.2/DESKTOP II

Prospective Validation Study of a Predictive Score for Operability of Recurrent Ovarian Cancer
The Multicenter Intergroup Study DESKTOP II. A Project of the AGO Kommission OVAR, AGO Study Group, NOGGO, AGO-Austria, and MITO


Harter P, Sehouli J, Reuss A, Hasenburg A, Scambia G, Cibula D, Mahner S, Vergote I, Reinthaller A, Burges A, Hanker L, Pölcher M, Kurzeder C, Canzler U, Petry K U, Obermair A, Petru E, Schmalfeldt B, Lorusso D, and du Bois A

 

Int J Gynecol Cancer 2011, 21: 289-295

 

 

AGO-OVAR OP.5/ROBOT

Surgical staging and prognosis in serous borderline ovarian tumours (BOT): A subanalysis of the AGO ROBOT study

 

F Trillsch, S Mahner, E Vettorazzi, L Woelber, A Reuss, K Baumann, M-D Keyver-Paik, U Canzler, K Wollschlaeger, D Forner, J Pfisterer, W Schroeder, K Muenstedt, B Richter, C Fotopoulou, B Schmalfeldt, A Burges, N Ewald-Riegler, N de Gregorio, F Hilpert, T Fehm, W Meier, P Hillemanns, L Hanker, A Hasenburg, H-G Strauss, M Hellriegel, P Wimberger, S Kommoss, F Kommoss, S Hauptmann and A du Bois

 

British Journal of Cancer (2015), 1-7 doi: 10.1038/bjc.2014.648, Advance Online Publication: 6 January 2015

 

 

Corrigendum to "Borderline tumours of the ovary: A cohort study of the Arbeitsgemeinschaft Gynäkologische Onkologie AGO Study Group" Eur J Cancer 49 (2013) 1905-1914

 

A du Bois, N Ewald-Riegler, N de Gregorio, A Reuss, S Mahner, C Fotopoulou, F Kommoss, B Schmalfeldt, F Hilpert T Fehm, A Burges, W Meier, P Hillemanns, L Hanker, A Hasenburg, H-G Strauss, M Hellriegel, P Wimberger, M-D Keyver-Paik, K Baumann, U Canzler, K Wollschlaeger, D Forner, J Pfisterer, W Schröder, K Münstedt, B Richter, S Kommoss, S Hauptmann

 

Eur J Cancer 65 (2016) 192-193

http://dx.doi.org/10.1016/j.ejca.2016.06.014 

 

 


 

Studien mit translationalem Schwerpunkt

 

AGO-TR 1

Prevalence of deleterious germline variants in risk genes including BRCA1/2 in consecutive ovarian cancer patients (AGO TR-1)

 

Harter P, Hauke J, Heitz F, Reuss A, Kommoss S, Marmé F, Heimbach A, Prieske K, Richters L, Burges A, Neidhardt G, de Gregorio N, El-Balat A, Hilpert F, Meier W, Kimmig R, Kast K, Sehouli J, Baumann K, Jackisch C, Park-Simon TW, Hanker L, Kröber S, Pfisterer J, Gevensleben H, Schnelzer A, Dietrich D, Neunhöffer T, Krockenberger M, Brucker SY, Nürnberg P, Thiele H, Altmüller J, Lamla J, Elser G, du Bois A, Hahnen E, Schmutzler R

 

PLoS ONE 12(10):e0186043, Published: October 20, 2017

https://doi.org/10.1371/journal.pone.0186043

 

 


 

Sonstige Veröffentlichungen

Advanced epithelial ovarian cancer: 1998 consensus statement

J.S. Berek, K. Bertelsen, A. du Bois, M.F. Brady, J. Carmichel, E.A. Eisenhauer, M. Gore, S. Grenman, T.C. Hamilton, S. W. Hansen, P.G. Harper, G. Horvath, S.B. Kaye, H.J. Lück, B. Lund, W.P. McGuire, J.P. Neijt, R.F. Ozols, M.K.B. Parmar, M.J. Piccart-Gebhart, R. van Rijswijk, P. Rosenberg, G.J.S. Rustin, C. Sessa, J.T. Thigpen, C. Tropé, M.K. Tuxen, I. Vergote, J.B. Vermorken, & P.H.B. Willemse

 

Ann Oncol 10 (suppl. 1): S87-S92 (1999)

 

 

Ist eine effiziente klinische Forschung in der gynäkologischen Onkologie in Deutschland möglich? Historie und aktueller Stand am Beispiel der AGO-Ovarialkarzinom-Studien. Eine Stellungnahme der AGO Studiengruppe Ovarialkarzinom

 

du Bois A, Studiengruppe Ovarialkarzinom der Arbeitsgemeinschaft gynäkologische Onkologie (AGO)

 

Forum DKG 14: 815-824 (1999)

 

 

Incidence of Venous Thromboembolism in Patients With Ovarian Cancer Undergoing Platinum/Paclitaxel-Containing First-Line Chemotherapie: An Exploratory Analysis by the Arbeitsgemeinschaft Gynaekologische Onkologie Ovarian Cancer Study Group

 

Christina Fotopoulou, Andreas du Bois, Alexandros N. Karavas, Ralf Trappe, Behnaz Aminossadati, Barbara Schmalfeldt, Jacobus Pfisterer and Jalid Sehouli

 

J Clin Oncol 26 (16): 2683-2689

 

 

Welchen Einfluss haben Klinikmerkmale auf die Prognose beim Ovarialkarzinom in Deutschland? Analyse des Zusammenhangs zwischen Klinikmerkmalen auf Therapiequalität und Ergebnisse beim Ovarialkarzinom in Deutschland.

 

A. du Bois, J. Rochon, C. Lamparter, J. Pfisterer für die AGO Organkommission OVAR

 

Zentralbl Gynakol 2005; 127: 18–30 · © J. A. Barth Verlag in Georg Thieme Verlag KG DOI 10.1055/s-2005-836290 ISSN 0044-4197

 

 

Die Therapie des fortgeschrittenen Ovarialkarzinoms in Deutschland: Welchen Einfluss hat die Teilnahme an klinischen Studien? Ergebnisse einer Umfrage der ORGANKOMMISSION OVAR der Arbeitsgemeinschaft Gynäkologische Onkologie (AGO) in der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe (DGGG) und der Deutschen Krebsgesellschaft (DKG)

 

A. du Bois, J. Pfisterer, Lenka Kellermann, R. Kreienberg

 

Geburtsh Frauenheilk 2001; 61: 863-871 © Thieme Verlag Stuttgart - New York - ISSN 0016-5751

 

 

QS-OVAR 2001

Das Qualitätssicherungsprogramm der AGO Organkommission OVAR (QS-OVAR): Versorgungsstruktur und Realität in Deutschland 2001

 

Analyse der Versorgungsstruktur und Qualität der Therapie des Ovarialkarzinoms in Deutschland. Untersuchung inwieweit die Therapieleitlinien umgesetzt werden, sowie Beschreibung von Prognosefaktoren.

 

A. du Bois, J. Rochon, C. Lamparter, J. Pfisterer

 

Zentralbl Gynakol 2005; 127: 9–17 · © J. A. Barth Verlag in Georg Thieme Verlag KG DOI 10.1055/s-2005-836289 ISSN 0044-4197

 

 

AGO-OVAR 3/QoL

Randomized Study of the Arbeitsgemeinschaft Gynaekologische Onkologie Ovarian Cancer Study Group Comparing Quality of Life in Patients With Ovarian Cancer Treated With Cisplatin/Paclitaxel Versus Carboplatin/Paclitaxel

 

Elfriede R. Greimel, Vesna Bjelic-Radisic, Jacobus Pfisterer, Felix Hilpert, Fedor Daghofer and Andreas du Bois

 

J Clin Oncol 24 (4): 579-586

 

 

AGO-OVAR 3 / Her-2/neu

Prognostic Value of Human Epidermal Growth Factor Receptor 2 (Her-2)/neu in Patients With Advanced Ovarian Cancer Treated With Platinum/Paclitaxel as First Line Chemotherapy. A Retrospective Evaluation of the AGO-OVAR 3 Trial by the AGO-OVAR Germany

 

Pfisterer J, du Bois A, Bentz EK, Kommoss F, Harter P, Huober J, Schmalfeldt B, Burchardi N, Arnold N, Hilpert F

 

Int J Gynecol Cancer 2009; 19:109-115

 

 

AGO-OVAR 14

Non-enrollment of ovarian cancer patients in clinical trials: Reasons and Backgrounds

 

Harter P, du Bois A, Schade-Brittinger C, Burges A, Wollschlaeger K, Gropp M, Schmalfeldt B, Huober J, Staehle A, Pfisterer J for the Study Coordination Group of the AGO-OVAR

 

Ann Oncol 16: 1801-1805, 2005

 

 

Neurotox

Neuroprotection with amifostine in the 1st-line treatment of advanced ovarian cancer with carboplatin/paclitaxel-based chemotherapy - a double-blind, placebo-controlled, randomized phase II-study from the AGO Ovarian Cancer Study Group

 

Hilpert F, Stähle A, Tomé O, Burges A, Rossner D, Späthe K, Heilmann V, Richter B and du Bois A for the Arbeitsgemeinschaft Gynäkologische Onkologie (AGO) ovarian cancer study group

 

Support Care Cancer 2005 Oct; 13(10): 797-805

 

 

Prognostic relevance of uncommon ovarian histology in women with stage III/IV epithelial ovarian cancer

Mackay H J, Brady M F, Oza A M, Reuss A, Pujade-Lauraine E, Swart A M, Siddiqui N, Colombo N, Bookman M A, Pfisterer J, du Bois A on behalf of the Gynecologic Cancer InterGroup (2010)

 

Int J Gynecol Cancer 20:945-952;2010

 

 

European network of gynaecological oncological trial groups' requirements for trials between academic groups and pharmaceutical companies

Vergote I, Pujade-Lauraine E, Pignata S, Kristensen GB, Ledermann J, Casado A, Sehouli J, Mirza M, Fossati R, Marth C, Creutzberg C, Del Campo J, Siddiqui N, Calvert P, Bamias A, Tulunay G, van der Zee AGJ, du Bois A

 

Int J Gynecol Cancer 20:476-478;2010

 

 

CA125 Early decline as a surrogate for progression-free survival in recurrent ovarian cancer

Lee CK, Friedlander M, Brown Ch, Gebski V, Georgopoulos A, Vergote I, Pignata S, Donadello N, Schmalfeldt B, Delva R, Mirza Mr, Sauthier P, Pujade-Lauraine E, Lord SJ, Simes J

 

J Natl Cancer Inst 2011;103:1-5

 

 

Decreased hypersensitivity reactions with carboplatin-pegylated liposomal doxorubicin compared to Carboplatin-paclitaxel combination: Analysis from the GCIG CALYPSO relapsing ovarian cancer trial

Joly F, Ray-Coquard I, Fabbro M, Donoghoe M, Bomann K, Sugimoto A, Vaughan M, Reinthaller A, Vergote I, Ferrandina G, Dell'Anna T, Huober J, Pujade-Lauraine E

 

Gyn Oncol 2011;122(2):226-32

 

 

Ovarian cancer in elderly patients: carboplatin and pegylated liposomal doxorubicin versus carboplatin and paclitaxel in late relapse: a GCIG CALYPSO sub-study

Kurtz JE, Kaminski MC, Floquet A, Veillard AS, Kimmig R, Dorum A, Elit L, Buck M, Petru E, Reed N, Scambia G, Varsellona N, Brown C, Pujade-Lauraine E on Behalf of Gynecologic Cancer Intergroup

 

Ann Oncol 2011 (Epub ahead of print)

 

 

The European network of Gynaecological Oncological Trial Groups

Vergote I, Pujade-Lauraine E, Pignata S, Kristensen GB, Ledermann J, Casado A, Sehouli J, Mirza M, Fossati R, Marth C, Ottevanger N, del Campo J, Siddiqui N, Calvert P, Bamias A, Tulunay G, Van der Zee AGJ, du Bois A

 

Clin.Invest. (2012) 2(1), 35-37

 

 

Treatment of Elderly Ovarian Cancer Patients in the Context of Controlled Clinical Trials: A Joint Analysis of the AGO Germany Experience

Hilpert F, Wimberger P, du Bois A, Pfisterer J, Harter P

 

Onkologie 2012;35:76–81

 

 

Roadmap for the European Network of Gynaecological Trial Groups (ENGOT) Trials

Ignace Vergote, MD, PhD, Gabriele Elser, RN, Benedicte Votan, MSc, Laura Farrelly, BSc(hons), RN, Joke De Roover, PhD, Jane Bryce, RN, MSN, Andreas du Bois, MD, PhD, and On Behalf of the member trial groups of the European Network of Gynaecological Trial groups (ENGOT)

 

Int J Gynecol Cancer 2013;23: 1339-1343

 

 

Specialized Pathology Review in Patients With Ovarian Cancer, Results From a Prospective Study

Stefan Kommoss, MD, Jacobus Pfisterer, MD, Alexander Reuss, MSc, Joachim Diebold, MD, Steffen Hauptmann, MD, Christine Schmidt, MD, Andreas du Bois, MD, Dietmar Schmidt, MD, and Friedrich Kommoss, MD

 

Int J Gynecol Cancer 2013;23: 1376-1382

  

 

Age-dependent differences in borderline ovarian tumours (BOT) regarding clinical characteristics and outcome: A sub-analysis of the Arbeitsgemeinschaft Gynaekologische Onkologie (AGO) ROBOT Study

Trillsch F, Mahner S, Woelber L, Vettarazzi E, Reiss A, Ewald-Riegler N, de Gregorio N, Fotopoulou C, Schmalfeldt B, Burges A, Hilpert F, Fehm T, Meier W, Hillemanns P, Hanker L, Hasenburg A, Strauss HG, Hellriegel M, Wimberger P, Baumann K, Keyver-Paik DM, Canzler U, Wollschlaeger K, Forner D, Pfisterer J, Schröder W, Münstedt K, Richter B, Kommoss F, Hauptmann S, du Bois A

 

Annals of Oncology 25:1320-1327.2014

 

 

Alopecia as surrogate marker for chemotherapy response in patients with primary epithelial ovarian cancer: A metaanalysis of four prospective randomised phase III trials with 5114 patients

Sehouli J, Fotopoulou C, Erol E, Richter R, Reuss A, Mahner S, Lauraine EP, Kristensen G, Herrstedt J, du Bois A, Pfisterer J.

 

Eur J Cancer. 2015.2015 May;51(7):825-32

 

 

The European Network for Gynaecological Oncological Trial Groups Charta for Privilegded Partnership

Marth C, du Bois A (ENGOG), Schauer C, du Bois A (AGO Study Group), Casado A, Vergote I, del Campo J, Goudopoulou A,
Pujade-Lauraine E, Bruchim I, Colombo N, Pignata S, Ledermann J, Glasspool R, Taskiran C, Fehr M, Cibula D

 

Int J Gynecol Cancer 2015;25: 1094-1095

 

 

European Network of Gynaecological Oncological Trial Groups’ Requirements for Trials Between Academic Groups and Industry Partners – First Update 2015

du Bois A, Reuss A, Pujade-Lauraine E, Pignata S, Ledermann J, Casado A, Sehouli J, Mirza M, Colombo N, Marth C, Witteveen E, del
Campo J, Calvert P, Aravantinos G, Vardar AM, van der Zee AGJ, Korach J, Taskiran C, Fehr M, Glasspool R, Pfisterer J, Cibula D, Vergote I and on behalf of the member trial groups of the European Network of Gynaecological Oncological Trial Groups (ENGOT)

 

Int J Gynecol Cancer 2015; Jun 9 Epub ahead of print

 

 

Quality of life and sexual function in patients with borderline tumors of the ovary. A substudy of the Arbeitsgemeinschaft Gynaekologische Onkologie (AGO) Study Group ROBOT-Study

Farthmann J, Hasenburg A, Weil M, Fotopoulou C, Ewald-Riegler N, du Bois O, Trillsch F, Mahner S, Strauss H-G, Wimberger P, Reuss A, du Bois A

 

Support Care Cancer, 23(1), 117-23

 

 

The FNTB promoter polymorphism rs11623866 as a potential predictive biomarker for lonafarib treatment of ovarian cancer patients

Bachmann HS, Meier W, du Bois A, Kimmig R, Kuhlmann JD, Siffert W, Sehouli J, Wollschlaeger K, Huober J, Hillemanns P, Burges A, Schmalfeldt B, Aminossadati B, Wimberger P

 

Br J Clin Pharmacol 2015 Nov; 80(5):1139-48. doi: 10.1111/bcp.12688. Epub 2015 Jul 22

 

 

Operability and chemotherapy responsiveness in advanced low-grade serous ovarian cancer. An analysis of the AGO Study Group Metadatabase

Grabowski J, Harter P, Heitz F, Pujade-Lauraine E, Reuss A, Kristensen G, Ray-Coquard I, Heitz J, Traut A, Pfisterer J, du Bois A

 

Gynecol Oncol 2016 Jan 22. pii: S0090-8258(16)30020-8. doi: 10.1016/j.ygyno.2016.01.022. Epub ahead of print

 

 

Statement of the AGO Kommission Ovar, AGO Study Group, NOGGO, AGO Austria and AGO Switzerland Regarding the Use of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Ovarian Cancer

P. Harter, A. du Bois, S. Mahner, J. Pfisterer, O. Ortmann, C. Marth, D. Fink, F. Hilpert, U. Wagner, J. Sehouli

 

Geburtsh Frauenheilk 2016; 76: 147-149

 

 

Prognostic factors in young ovarian cancer patients: An analysis of four prospective phase III intergroup trials of the AGO Study Group, GINECO and NSGO

Klar M, Hasenburg A, Hasanov M, Hilpert F, Meier W, Pfisterer J, Pujade-Lauraine E, Herrstedt J, Reuss A, du Bois A

 

European Journal of Cancer: Volume 66, October 2016, Pages 114-124

http://dx.doi.org/10.1016/j.ejca.2016.07.014

 

 

Prognostic and predictive effects of primary versus secondary platinum resistance for bevacizumab treatment for platinum-resistant ovarian cancer in the AURELIA trial

F. Trillsch, S. Mahner, F. Hilpert, L. Davies, E. García-Martínez, G. Kristensen, A. Savarese, P, Vuylsteke, M. Los, F. Zagouri, L. Gladieff, J. Sehouli, C. Khoon Lee, V. Gebski & E. Pujade-Lauraine

 

Annals of Oncology 27: 1733-1739, 2016

doi.10.1093/annonc/mdw236

Published online 10 June 2016

 

 

Better resource utilization and quality of care for ovarian cancer patients using internet-based pathology review

Kommoss S, Kommoss F, Diebold J, Lax S, Schmid D, Staebler A, du Bois A, Pfisterer J

 

British Journal of Cancer 116, 287-292 (31 January 2017)

doi:10.1038/bjc.2016.416

 

 


 

GCIG Rare Tumor Working Group - Publikationen

 

Ovarialkarzinom

 

Gynecologic Cancer InterGroup (GCIG) consensus review for ovarian tumors of low malignant potential (borderline ovarian tumors)

Harter P, Gershenson D, Lhomme C, Lecuru F, Ledermann J, Provencher DM, Mezzanzanica D, Quinn M, Maenpaa J, Kim JW, Mahner S, Hilpert F, Baumann K, Pfisterer J, du Bois A.

Int J Gynecol Cancer. 2014 Nov; 24:S5-S8

 

Gynecologic Cancer Inter Group (GCIG) consensus review for ovarian and primary peritoneal low-grade serous carcinomas

Gourley C, Farley J, Provencher DM, Pignata S, Mileshkin L, Harter P, Maenpaa J, Kim JW, Pujade-Lauraine E, Glasspool RM, Ray-Coquard I, Gershenson D.

Int J Gynecol Cancer. 2014 Nov; 24:S9-S13

 

Gynecologic Cancer InterGroup (GCIG) consensus review for mucinous ovarian carcinoma

Ledermann JA, Luvero D, Shafer A, O'Connor D, Mangili G, Friedlander M, Pfisterer J, Mirza MR, Kim JW, Alexandre J, Oza A, Brown J.

Int J Gynecol Cancer. 2014 Nov;24:S14-S19

 

Gynecologic Cancer InterGroup (GCIG) consensus review for clear cell carcinoma of the ovary

Okamoto A, Glasspool RM, Mabuchi S, Matsumura N, Nomura H, Itamochi H, Takano M, Takano T, Susumu N, Aoki D, Konishi I, Covens A, Ledermann J, Mezzanzanica D, Steer C, Millan D, McNeish IA, Pfisterer J, Kang S, Gladieff L, Bryce J, Oza A.

Int J Gynecol Cancer. 2014 Nov;24:S20-S25

 

Gynecologic Cancer InterGroup (GCIG) consensus review for squamous cell carcinoma of the ovary

Glasspool RM, Gonzáles Martín A, Millan D, Lorusso D, Åvall-Lundquvist E, Hurteau JA, Davis A, Hilpert F, Kim JW, Alexandre J, Ledermann JA.

Int J Gynecol Cancer. 2014 Nov;24:S26-S29

 

Gynecologic Cancer InterGroup (GCIG) consensus review for ovarian small cell cancers

Reed NS, Pautier P, Åvall-Lundqvist E, Choi CH, du Bois A, Friedlander M, Fyles A, Kichenadasse G, Provencher DM, Ray-Coquard I.

Int J Gynecol Cancer. 2014 Nov; 24:S30-S34

 

Gynecologic Cancer InterGroup (GCIG) consensus review for carcinoid tumors of the ovary

Reed NS, Gomez-Garcia E, Gallardo-Rincon D, Barrette B, Baumann K, Friedlander M, Kichenadasse G, Kim JW, Lorusso D, Mirza MR, Ray-Coquard I.

Int J Gynecol Cancer. 2014 Nov;24:S35-S41

 

Gynecologic Cancer InterGroup (GCIG) consensus review for ovarian sex cord stromal tumors

Ray-Coquard I, Brown J, Harter P, Provencher DM, Fong PC, Maenpaa J, Ledermann JA, Emons G, Rigaud DB, Glasspool RM, Mezzanzanica D, Colombo N.

Int J Gynecol Cancer. 2014 Nov;24:S42-S47

 

Gynecologic Cancer Intergroup (GCIG) consensus review for ovarian germ cell tumors

Brown J, Friedlander M, Backes FJ, Harter P, O'Connor DM, die la Motte Rouge T, Lorusso D, Maenpaa J, Kim JW, Tenney ME, Seckl MJ

 

5th Ovarian Cancer Consensus Conference of the Gynecologic Cancer InterGroup: first-line interventions

Karam A, Ledermann JA, Kim JW, Sehouli J, Lu K, Gourley C, Katsumata N, Burger RA, Nam BH, Bacon M, Ng C, Pfisterer J, Bekkers RL, Casado Herráez A, Redondo A, Fujiwara H, Gleeson N, Rosengarten O, Scambia G, Zhu J, Okamoto A, Stuart G, Ochiai K, participants of the 5th Ovarian Cancer Consensus Conference

Ann Oncol 2017 Apr 1;28(4):711-717

 

5th Ovarian Cancer Consensus Conference of the Gynecologic Cancer InterGroup: Individualized Therapy and Patient Factors

McGee J, Bookman M, Harter P, Marth C, McNeish I, Moore KN, Poveda A, Hilpert F, Hasegawa K, Bacon M, Gatsonis C, Brand A, Kridelka F, Berek J, Ottevanger N, Levy T, Silverberg S, Kim BG, Hirte H, Okamoto A, Stuart G, Ochiai K; on behalf of the participants of the 5th Ovarian Cancer Consensus Conference

Ann Oncol 2017 Apr 1;28(4):702-710

 

5th Ovarian Cancer Consensus Conference of the Gynecologic Cancer InterGroup: Recurrent Disease

Wilson MK, Pujade-Lauraine E, Aoki D, Mirza MR, Lorusso D, Oza AM, du Bois A, Vergote I, Reuss A, Bacon M, Friedlander M, Rincon D, Joly F, Chang SJ, Ferrero AM, Edmondson RJ, Wimberger P, Maenpaa J, Gaffney D, Zhang R, Okamoto A, Stuart G, Ochiai K; participants of the 5th Ovarian Cancer Consensus Conference

Ann Oncol 2017 Apr 1;28(4):727-732

 

5th Ovarian Cancer Consensus Conference of the Gynecologic Cancer InterGroup: Clinical trial design for rare ovarian tumours

Leary AF, Quinn M, Fujiwara K, Coleman RL, Kohn E, Sugiyama T, Glasspool R, Ray-Coquard I, Colombo N, Bacon M, Zeimet A, Westermann A, Gomez-Garcia E, Provencher D, Welch S, Small W, Millan D, Okamoto A, Stuart G, Ochiai K; participants of the 5th Ovarian Cancer Consensus Conference

Ann Oncol 2017 Apr 1;28(4):718-726

 

Karzinosarkom Uterus und Ovar

 

Gynecologic Cancer InterGroup (GCIG) consensus review for uterine and ovarian carcinosarcoma

Berton-Rigaud D, Devouassoux-Shisheboran M, Ledermann JA, Leitao MM, Powell MA, Poveda A, Beale P, Glasspool RM, Creutzberg CL, Harter P, Kim JW, Reed NS, Ray-Coquard I

Int J Gynecol Cancer. 2014 Nov;24:S55-S60

 

Gynecologic Cancer InterGroup (GCIG) consensus review: uterine and ovarian leiomyosarcomas

Hensley ML, Barette BA, Baumann K, Gaffney D, Hamilton AL, Kim JW, Maenpaa JU, Pautier P, Siddiqui NA, Westermann AM, Ray-Coquard I.

Int J Gynecol Cancer. 2014 Nov;24:S61-S66

 

Endometrium- und Zervixkarzinome

 

Gynecologic Cancer InterGroup (GCIG) consensus review for endometrial stromal sarcoma

Amant F, Floquet A, Friedlander M, Kristensen G, Mahner S, Nam EJ, Powell MA, Ray-Coquard I, Siddiqui N, Sykes P, Westermann AM, Seddon B.

Int J Gynecol Cancer. 2014 Nov;24:S67-S72

 

Gynecologic Cancer InterGroup (GCIG) consensus review for high-grade undifferentiated sarcomas of the uterus

Pautier P, Nam EJ, Provencher DM, Hamilton AL, Mangili G, Siddiqui NA, Westermann AM, Reed NS, Harter P, Ray-Coquard I.

Int J Gynecol Cancer. 2014 Nov;24:S73-S77

 

Gynecologic Cancer InterGroup (GCIG) consensus review for mullerian adenosarcoma of the female genital tract

Friedlander ML1, Covens A, Glasspool RM, Hilpert F, Kristensen G, Kwon S, Selle F, Small W, Witteveen E, Russell P.

Int J Gynecol Cancer. 2014 Nov;24:S78-S82

 

Gynecologic Cancer InterGroup (GCIG) consensus review for uterine serous carcinoma

Sagae S, Susumu N, Viswanathan AN, Aoki D, Backes FJ, Provencher DM, Vaughan M, Creutzberg CL, Kurzeder C, Kristensen G, Lee C, Kurtz JE, Glasspool RM, Small W Jr.

Int J Gynecol Cancer. 2014 Nov;24:S83-S89

 

Gynecologic Cancer InterGroup (GCIG) consensus review for clear cell carcinoma of the uterine corpus and cervix

Hasegawa K, Nagao S, Yasuda M, Millan D, Viswanathan AN, Glaspool RM, Devouassoux-Shisheboran M, Covens A, Lorusso D, Kurzeder C, Kim JW, Gladieff L, Bryce J, Friedlander M, Fujiwara K

Int J Gynecol Cancer. 2014 Nov;24:S90-S95

 

Gynecologic Cancer InterGroup (GCIG) consensus review for cervical adenocarcinoma

Fujiwara H, Yokota H, Monk B, Treilleux I, Devouassoux-Shisheboran M, Davis A, Kim JW, Mahner S, Stany M, Pignata S, Ray-Coquard I, Fujiwara K

Int J Gynecol Cancer. 2014 Nov;24:S96-S101

 

Gynecologic Cancer InterGroup (GCIG) consensus review for small cell carcinoma of the cervix

Satoh T, Takei Y, Treilleux I, Devouassoux-Shisheboran M, Ledermann J, Viswanathan AN, Mahner S, Provencher DM, Mileshkin L, Åvall-Lundqvist E, Pautier P, Reed NS, Fujiwara K.

Int J Gynecol Cancer. 2014 Nov;24:S102-S108

 

Andere seltene gynäkologische Tumore

 

Trophoblastic disease review for diagnosis and management: a joint report from the International Society for the Study of Trophoblastic Disease, European Organisation for the Treatment of Trophoblastic Disease, and the Gynecologic Cancer InterGroup

Mangili G, Lorusso D, Brown J, Pfisterer J, Massuger L, Vaughan M, Ngan HY, Golfier F, Sekharan PK, Charry RC, Poveda A, Kim JW, Xiang Y, Berkowitz R, Seckl MJ

Int J Gynecol Cancer. 2014 Nov;24:S109-S116

 

Gynecologic Cancer InterGroup (GCIG) consensus review for vulvovaginal melanomas

Leitao MM Jr, Cheng X, Hamilton AL, Siddiqui NA, Jurgenliemk-Schulz I, Mahner S, Åvall-Lundqvist E, Kim K, Freyer G.

Int J Gynecol Cancer. 2014; Nov24:S117-S122

 

 

 

 

 

 

 

 

 

 

 

 

 

 

English Version | Sitemap | Suche | Impressum | Kontakt

© 2011 AGO Research GmbH | Admin-Login | Webdesign Hamburg